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Pesticide usage in agriculture has occurred for centuries and led to significant positive outcomes in food production and noticeable reduction in crop losses. However, pesticide usage on food crops often results in the presence of toxic pesticide residues on food produce, which is the main route of exposure to pesticides in humans. The toxicity of the pesticide residues can potentially cause debilitating effects to major human organs and body systems. Pesticide residue analysis addresses the issue of pesticide residues in foods by screening and quantifying the levels of pesticides in food commodities.
Benzylideneanilines, the condensation products of benzaldehyde and aniline derivatives, have enjoyed significant success as optical metal ion sensors due to their ability to form stable metal complexes which exhibit distinct spectral features compared to the unbound compound. However, their use in aqueous media is limited by the hydrolytic susceptibility of the C=N moiety. Hence, an in-depth investigation into the hydrolytic degradation mechanism of a series of 2-aminophenol derived Nbenzylideneanilines was conducted wherein molecular modelling techniques were applied to elucidate the “step-by-step” transformation mechanism of these compounds from a fundamental perspective.
In recent years there has been a resurgence in interest in psychedelic assisted psychotherapy (PAP) [1]. Initial scientific research into the utilization of these compounds were eventually suspended due to concerns related to increasing recreational use of psychedelics and their association with the rise of the “counterculture movement” in the United States [2]. However, the use of psilocybin and other psychedelics have shown promise in the treatment of mental illnesses. The efficacy of this modality of treatment has been demonstrated through clinical trials and other studies in the management of a number of mental illnesses, including some treatment resistant cases [3].
Vector-borne diseases have since the 17th century been the leading cause of death by disease more than any other causes combined, even preventing development in the tropics (Gubler 1998). Of all insect vectors, Aedes aegypti proves to be the deadliest as it is the primary vector of the four most notorious vector-borne diseases – chikungunya (chik-V), Zika (Zik-V), dengue fever and yellow fever viruses. Control of the spread of Aedesborne diseases is primarily reliant on the control of the vector responsible for their spread. Traditionally, vector control relied on environmental hygiene and the elimination of breeding sites (Gubler 1998), shifting only in the 1980s to the use of synthetic chemicals in the form of carbamate, organochloride, organophosphate and pyrethroid insecticides (Norris, et al. 2015). However, the evolution of Aedes aegypti resistance to synthetic chemicals have made control of the spread of the vector and its diseases increasingly difficult. This led to the exploration of innovative and alternative methods in the control of Aedes aegypti.
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